MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
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1 Blood pressure-lowering effect of simvastatin: a placebo-controlled randomized clinical trial with 24-h ambulatory blood pressure monitoring Journal of Human Hypertension, May 23, 2013 Clinical Article
2 Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials International Journal of Stroke, May 23, 2013 Clinical Article
3 Impact of onset-to-reperfusion time on stroke mortality Circulation, May 23, 2013 Clinical Article
4 Role of aspiration and mechanical thrombectomy in patients with acute myocardial infarction undergoing primary angioplasty: An updated meta-analysis of randomized trials JACC - Journal of the American College of Cardiology, May 23, 2013 Evidence Based Medicine Review Article Clinical Article
5 Bevacizumab - finding its niche in the treatment of heart failure secondary to liver vascular malformations in hereditary hemorrhagic telangiectasia Hepatology, May 23, 2013 Review Article
6 Gender difference in statin intervention on blood lipid control among patients with coronary heart disease Full Text International Journal of Gerontology, May 23, 2013 Clinical Article
7 Are users of sulfonylureas at the time of an acute coronary syndrome at risk of poorer outcomes? Diabetes, Obesity and Metabolism, May 23, 2013 Clinical Article
8 LDL cholesterol in CKD-to treat or not to treat? Kidney International, May 23, 2013 Clinical Article
9 Outcome of percutaneous coronary intervention with drug-eluting stents in unprotected left main versus non-left main native coronary artery disease: results from the prospective multicenter German DES.DE registry Clinical Research in Cardiology, May 23, 2013 Clinical Article
10 Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control Circulation, May 23, 2013 Clinical Article
11 Identification of candidate genes encoding an LDL-C QTL in baboons Journal of Lipid Research, May 23, 2013 Clinical Article
12 Left Atrial Massive Thrombus Formation on the Transseptal Sheath Despite Adequate Anticoagulation with Warfarin and Heparin During Pulmonary Vein Isolation Journal of Cardiovascular Electrophysiology, May 23, 2013
13 Occurrence of Steam Pops during Irrigated RF Ablation: Novel Insights from Microwave Radiometry Journal of Cardiovascular Electrophysiology, May 23, 2013 Clinical Article
14 Predicting risk of coronary events and all-cause mortality: role of B-type natriuretic peptide above traditional risk factors and coronary artery calcium scoring in the general population: the Heinz Nixdorf Recall Study European Journal of Preventive Cardiology, May 23, 2013 Clinical Article
15 Percutaneous Endocardial Occlusion of Incompletely Surgically-Ligated Left Atrial Appendage Journal of Cardiovascular Electrophysiology, May 23, 2013 Clinical Article
16 Frailty is independently associated with 1-year mortality for elderly patients with non-ST-segment elevation myocardial infarction European Journal of Preventive Cardiology, May 23, 2013 Clinical Article
17 Erectile dysfunction may be the first clinical sign of insulin resistance and endothelial dysfunction in young men Clinical Research in Cardiology, May 23, 2013 Clinical Article
18 Intracoronary Injection of Bone Marrow–Derived Mononuclear Cells Early or Late After Acute Myocardial Infarction Circulation, May 23, 2013 Clinical Article
19 Urinary flavonoid excretion and risk of acute coronary syndrome in a nested case-control study American Journal of Clinical Nutrition, May 23, 2013 Clinical Article
20 Ventricular pressure–volume loops obtained by 3D real-time echocardiography and mini pressure wire—a feasibility study Clinical Research in Cardiology, May 23, 2013 Clinical Article
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryAs published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryAs published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summary1 Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) JACC - Journal of the American College of Cardiology, April 3, 2013
2 Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry American Heart Journal, April 1, 2013
3 The long QT syndrome: a transatlantic clinical approach to diagnosis and therapy European Heart Journal, April 9, 2013 Review Article
4 Effect of coenzyme q10 supplementation on statin-induced myalgias The American Journal of Cardiology, July 30, 2012
5 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013
6 Statins and autoimmunity Immunologic Research, April 17, 2013 Review Article
7 Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol, Bisoprolol, Metoprolol, and Nebivolol) The American Journal of Cardiology, February 26, 2013 Evidence Based Medicine Review Article
8 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
9 Clinical Update on the Management of Atrial Fibrillation Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 10, 2013
10 Treatment of Hypertension Among African Americans: The Jackson Heart Study The Journal of Clinical Hypertension, April 5, 2013
11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article
13 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
14 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article
15 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 2, 2013 Free full text
16 Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study JACC - Journal of the American College of Cardiology, April 12, 2013
17 Combination therapy in the management of pulmonary arterial hypertension International Journal of Clinical Practice, April 15, 2013 Review Article
18 A double-blind, double-dummy, randomized, placebo-controlled trial to evaluate the effect of statin therapy on triglyceride levels in Mexican hypertriglyceridemic patients Current Medical Research and Opinion, April 16, 2013
19 Long-term clinical follow-up of the multicenter, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, April 11, 2013
20 Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure? Congestive Heart Failure, April 2, 2013 Free full text
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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