We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Efficacy of Mitral Valve Repair as an Adjunct Procedure to Coronary Artery Bypass Grafting in Moderate Ischemic Mitral Regurgitation: A Meta-Analysis of Randomized TrialsJournal of Cardiac Surgery, July 02, 2015  Clinical Article  Evidence Based Medicine  Review Article
2Comparison of three diuretic treatment strategies for patients with acute decompensated heart failureHerz, July 02, 2015  Clinical Article
3Dobutamine therapy is associated with worse clinical outcomes compared with nesiritide therapy for acute decompensated heart failure: a systematic review and meta-analysisAmerican Journal of Cardiovascular Drugs, July 02, 2015  Clinical Article  Evidence Based Medicine  Review Article
4Rs7193343 polymorphism in zinc finger homeobox 3 (ZFHX3) gene and atrial fibrillation: an updated meta-analysis of 10 case-control comparisonsBMC Cardiovascular Disorders, July 02, 2015  Full Text  Clinical Article
5Cost effectiveness of antiplatelet and antithrombotic therapy in the setting of acute coronary syndrome: current perspective and literature reviewAmerican Journal of Cardiovascular Drugs, July 02, 2015  Clinical Article
6Angiotensin II receptor blocker neprilysin inhibitor (arni): new avenues in cardiovascular therapyHigh Blood Pressure & Cardiovascular Prevention, July 02, 2015  Clinical Article
7Prime mover or fellow traveller: 25-hydroxy vitamin D’s seasonal variation, cardiovascular disease and death in the Scottish Heart Health Extended Cohort (SHHEC)International Journal of Epidemiology, July 02, 2015  Clinical Article
8Antiplatelet therapy during PCI for patients with stable angina and atrial fibrillationCurrent Cardiology Reports, July 02, 2015  Clinical Article
9Cost-effectiveness analysis of rivaroxaban in the secondary prevention of acute coronary syndromes in swedenCardiology and Therapy, July 02, 2015  Full Text
10Remote ischemic conditioning for preventing contrast-induced acute kidney injury in patients undergoing percutaneous coronary interventions/coronary angiography: a meta-analysis of randomized controlled trialsJournal of Cardiovascular Pharmacology and Therapeutics, July 02, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1UCLA doctors use 3-D printed model to guide tricky heart valve replacementUCLA Health System, July 02, 2015
2Enzyme provides built-in protection against atherosclerosisUniversity of Michigan Health System, July 02, 2015
3CPR app's network saves lives, but needs buy-in from publicUW Medicine, July 02, 2015
4PTSD raises odds of heart attack and stroke in womenHarvard School of Public Health News, July 02, 2015
5Half of all heart disease deaths could be prevented, study findsEmory's Woodruff Health Sciences Center News, July 01, 2015
6PTSD, traumatic experiences may raise heart attack, stroke risk in womenAmerican Heart Association News, July 01, 2015
7Sugary drinks linked to high death tolls worldwideTufts University News, July 01, 2015
8New recommendations for LAA occlusion devices releasedAmerican College of Cardiology News, July 01, 2015
9ACC council addresses cardiac arrest in non-STEMI patientsAmerican College of Cardiology News, July 01, 2015
10Umbilical cord ‘milking’ improves blood flow in preterm infantsPediatrics, June 30, 2015

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Rho-associated kinase activity is a biomarker for cardiovascular events

As reported in Hypertension, rho-associated kinase activity is an independent predictor of cardiovascular events. The study involved 633 patients undergoing routine health screening examinations with a median follow-up of 42 months. There were 29 cardiovascular-related deaths, 2 myocardial infarctions, 20 revascularizations, 15 strokes, and 17 hospitalizations for heart failure. The HRs for first cardiovascular event, death, stroke, and revascularization were 2.19, 2.57, 2.14, and 2.68, respectively.

Relationship benefit in women with IHD

As reported in BMC Medicine, women who were married or living with a partner had a decreased risk of mortality (RR=0.72) after the first ischemic heart disease (IHD) event compared to women who were not married or living with a partner. The study involved 734626 women with no history of IHD who were followed for 8.6 y; there were 30747 women with a first IHD event and 2148 deaths.

Muscle strength in adolescence decreases CVD risk

As reported in BMC Medicine, adolescents (n=38588) with the highest tertile of muscle strength had a decreased risk of CVD (HR=0.88) compared to adolescents with the lowest tertile of muscle strength after 42 y of follow-up. Of note, low muscle strength in adolescence by itself had no effect on CVD risk in middle age (HR=0.99). In contrast, high muscle strength in adolescence significantly decreased the risk of CVD in middle age (HR=1.31).

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Clinical Pearls

Clinical Pearl from Smartest DocFlecainide use in children with cardiomyopathy or structural heart disease has increased in recent years.

Clinical Pearl from Smartest DocPersistent functional mitral regurgitation tends to be associated with an increased incidence of HF events in patients with severe aortic insufficiency undergoing AVR.

Clinical Pearl from Smartest DocProcedural success is obtained less frequently following percutaneous mitral commissurotomy in patients with calcified commissures, but success can be safely achieved in a large proportion of patients.

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