Statin use associated with decreased mortality in HFPEF
Based on a meta-analysis reported in the American Journal of Cardiology, statin use by patients (n=17985) with heart failure with preserved ejection fraction (HFPEF) is associated with a 40% reduction in mortality.
Fructosamine and glycated albumin predict incident diabetes
As reported in The Lancet, fructosamine and glycated albumin > 95th percentile predicted incident diabetes (HR=4.96 and 6.17, respectively) and retinopathy and chronic kidney disease among 958 and 11348 patients with and without diabetes, respectively, followed for 20 years.
Rho-associated kinase activity is a biomarker for cardiovascular events
As reported in Hypertension, rho-associated kinase activity is an independent predictor of cardiovascular events. The study involved 633 patients undergoing routine health screening examinations with a median follow-up of 42 months. There were 29 cardiovascular-related deaths, 2 myocardial infarctions, 20 revascularizations, 15 strokes, and 17 hospitalizations for heart failure. The HRs for first cardiovascular event, death, stroke, and revascularization were 2.19, 2.57, 2.14, and 2.68, respectively.