1Effect of high dose statin pretreatment on endothelial progenitor cells after percutaneous coronary intervention (HIPOCRATES study)Cardiovascular Drugs and Therapy  Clinical Article
2Differences in patient outcomes after conventional versus real time perfusion stress echocardiography in men versus women: a prospective randomised trialHeart  Clinical Article  Evidence Based Medicine
3Aspirin therapy is associated with less compact fibrin networks and enhanced fibrinolysis in patients with abdominal aortic aneurysmJournal of Thrombosis and Haemostasis  Clinical Article
4The difference between Asian and Western in the effect of LDL-C lowering therapy on coronary atherosclerotic plaque: a meta-analysis reportBMC Cardiovascular Disorders  Full Text  Clinical Article  Evidence Based Medicine
5Anticoagulant reversal, blood pressure levels, and anticoagulant resumption in patients with anticoagulation-related intracerebral hemorrhageJAMA  Clinical Article
6Serum 25-hydroxyvitamin D is associated with major cardiovascular risk factors and cardiac structure and function in patients with coronary artery diseaseNutrition, Metabolism & Cardiovascular Diseases  Clinical Article
7Comparison of three dimensional proximal isovelocity surface area to cardiac magnetic resonance imaging for quantifying mitral regurgitationThe American Journal of Cardiology  Review Article
8Long-term results of a randomized controlled trial analyzing the role of systematic pre-operative coronary angiography before elective carotid endarterectomy in patients with asymptomatic coronary artery diseaseEuropean Journal of Vascular and Endovascular Surgery  Clinical Article
9Association of NSAID use with risk of bleeding and cardiovascular events in patients receiving antithrombotic therapy after myocardial infarctionJAMA  Clinical Article  Evidence Based Medicine
10Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapyThe American Journal of Cardiology  Clinical Article
1Heart failure patients struggling with daily tasks more often hospitalized; die earlyAmerican Heart Association News
2Sleeping over eight hours a day associated with greater risk of strokeUniversity of Cambridge News
3NewYork-Presbyterian Hospital/Columbia University Medical Center participates in national clinical trial for heart pump deviceNewYork-Presbyterian
4Million man study examines long-term effects of blocking inflammationUniversity of Cambridge News
5NewYork-Presbyterian Hospital participating in trial of device designed to prevent stroke in heart valve-replacement patientsNewYork-Presbyterian
6Homeless people with mental illness also have significantly higher 30-year risk of serious cardiovascular disease, research findsSt. Michael's Hospital
7Keep calm, anger can trigger a heart attack!The University of Sydney News
8Younger women delay seeking help for heart attacks, study findsYale School of Medicine News
9Women's heart disease should be a research priorityAmerican Heart Association News
106 Year study identifies patients at higher risk of recurrent strokeUniversity of Illinois Hospital & Health Sciences System

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Vitamin D supplementation improves ejection fraction

As reported in Nutrition, Metabolism, and Cardiovascular Diseases, vitamin D supplementation (4000 IU/d of cholecalciferol x 6 months) of vitamin D-deficient heart failure patients (n=23) resulted in an increase in the ejection fraction compared to placebo (6.7 vs. -4.3%).

Fructosamine and glycated albumin predict incident diabetes

As reported in The Lancet, fructosamine and glycated albumin > 95th percentile predicted incident diabetes (HR=4.96 and 6.17, respectively) and retinopathy and chronic kidney disease among 958 and 11348 patients with and without diabetes, respectively, followed for 20 years.

AGEs increase cardiovascular risk in T2DM

As reported in Diabetes, elevated advanced glycation end products increase the risk for incident cardiovascular events (HR=1.31) in type 2 diabetics (n=218).

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Clinical Pearls

Clinical Pearl from Smartest DocSlow ultrafiltration by peritoneal dialysis may relieve fluid overload without compromising cardiac output in patients with CHF.

Clinical Pearl from Smartest DocSwitching to dabigatran increases stroke/TIA rate among warfarin-experienced patients with a history of stroke or TIA.

Clinical Pearl from Smartest DocRisk of non-embolic stroke is highest in patients with metabolic syndrome and overt diabetes.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List