Vitamin D supplementation improves ejection fraction
As reported in Nutrition, Metabolism, and Cardiovascular Diseases, vitamin D supplementation (4000 IU/d of cholecalciferol x 6 months) of vitamin D-deficient heart failure patients (n=23) resulted in an increase in the ejection fraction compared to placebo (6.7 vs. -4.3%).
AGEs increase cardiovascular risk in T2DM
As reported in Diabetes, elevated advanced glycation end products increase the risk for incident cardiovascular events (HR=1.31) in type 2 diabetics (n=218).
Statin use associated with decreased mortality in HFPEF
Based on a meta-analysis reported in the American Journal of Cardiology, statin use by patients (n=17985) with heart failure with preserved ejection fraction (HFPEF) is associated with a 40% reduction in mortality.