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Anesthesiology - Basic Science/Genetics News & Articles
MDLinx.com, your #1 source for Anesthesiology medical news articles, journals, and clinical articles. The diligent team of medical editors at MDLinx rank, sort and summarize articles with topical coverage ranging from: Pain Management, Critical Care, Trauma, Regional Anesthesia, Perianesthesia and monitoring to Economics of Medicine and much more.
On this page you may also read bonus content personally chosen by our Physician Editor, D. Scott Cunningham MD, PHD, and clinical pearls from our Smartest Doc Physician Review courses.
Become an MDLinx.com member today and take full advantage of these benefits in addition to updates on Anesthesiology conferences, jobs and specialty specific newsletters. Also earn honoraria by participating in Market Research opportunities.
Your Unread Messages in Anesthesiology
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Articles
Latest (1) Full Text Articles (75)161 Anti-N-Methyl-d-Aspartate Receptor Encephalitis and Its Anesthetic Implications Anesthesia & Analgesia, October 28, 2011
162 mRNA-based approach to monitor recombinant gamma-interferon restoration of LPS-induced endotoxin tolerance Critical Care, October 27, 2011
163 Screening of the Ryanodine 1 Gene for Malignant Hyperthermia Causative Mutations by High Resolution Melt Curve Analysis Anesthesia & Analgesia, October 25, 2011
164 Critical illness induces alternative activation of M2 macrophages in adipose tissue Critical Care, October 24, 2011
165 Late onset congenital central hypoventilation syndrome after exposure to general anesthesia Canadian Journal of Anesthesia, October 19, 2011
166 Persistent pain after mastectomy with reconstruction Journal of Clinical Anesthesia, October 17, 2011
167 Respiration: control of ventilation Anaesthesia & intensive care medicine, October 11, 2011
168 Serial increase of interleukin-12 response and HLA-DR expression in severe sepsis survivors Critical Care, October 4, 2011
169 The Intrathecally Administered Kappa-2 Opioid Agonist GR89696 and Interleukin-10 Attenuate Bone Cancer-Induced Pain Through Synergistic Interaction Anesthesia & Analgesia, September 29, 2011
170 Perioperative Exacerbation of Valproic Acid-Associated Hyperammonemia: A Clinical and Genetic Analysis Anesthesia & Analgesia, September 28, 2011
171 Leptin and leptin receptor polymorphisms are associated with poor outcome (death) in patients with non-appendicular secondary peritonitis. Critical Care, September 27, 2011
172 Deleterious Impact of a gamma-Aminobutyric Acid Type A Receptor Preferring General Anesthetic When Used in the Presence of Persistent Inflammation Full Text Anesthesiology, September 22, 2011
173 Polymyxin B-Immobilized Fiber Column Hemoperfusion Therapy for Septic Shock Shock, September 21, 2011
174 Novel Hyperactive Glucocorticoid Receptor Isoform Identified Within a Human Population Shock, September 20, 2011
175 Local anesthetics and their adjuncts Paediatric Anaesthesia, September 19, 2011
176 Diagnosis of congenital myasthenic syndrome with mutation of the RAPSN gene after general anaesthesia European Journal of Anaesthesiology, September 16, 2011
177 Common Variants of the ACE Gene and Aneurysmal Subarachnoid Hemorrhage in a Danish Population: A Case-control Study Journal of Neurosurgical Anesthesiology , September 15, 2011
178 Isoflurane decreases death of human embryonic stem cell-derived, transcriptional marker Nkx2.5+ cardiac progenitor cells Acta Anaesthesiologica Scandinavica, September 9, 2011
179 The effect of beta1-adrenergic receptor gene polymorphism on prolongation of corrected QT interval during endotracheal intubation under sevoflurane anesthesia Full Text Korean Journal of Anesthesiology, September 6, 2011 Clinical Article
180 Peroxisome Proliferator-Activated Receptor gamma Agonist Troglitazone Inhibits High Mobility Group Box 1 Expression in Endothelial Cells Via Suppressing Transcriptional Activity of Nuclear Factor kappa B and Activator Protein 1 Shock, September 2, 2011
Clinical Pearls in Anesthesiology
- Epidural anesthesia improves postoperative respiratory function compared with general anesthesia in patients with COPD undergoing abdominal aortic aneurysm repair.
- According to the American Society of Anesthesiologists guidelines for chronic pain management, acupuncture may be considered as adjuvant therapy to conventional therapy in patients with nonspecific, non-inflammatory low back pain.
- Recent evidence shows preoperative anxiety has a significant effect on hypotension after spinal anesthesia
Highlights in Anesthesiology
Dopamine is associated with increased mortality in septic shock
Based on a meta-analysis of 11 trials involving 2,768 patients with septic shock, treatment with dopamine was associated with a greater risk of 28-day mortality (RR=1.12-1.23) and arrhythmias (RR=2.34) than norepinephrine.
Read the article summaryRBC transfusion decreased mortality in sepsis
As published in Critical Care Medicine, RBC transfusion decreases the risk of mortality in patients with sepsis and septic shock. The study involved 1054 patients in 22 ICUs and SICUs at 12 teaching hospitals in Korea. Of the 1054 patients, 407 received RBC transfusions; the mean pre-transfusion hemoglobin level was 7.7 g/dL. The transfused patients had a lower risk of 7-day (HR = 0.42), 28-day (HR = 0.43), and in-hospital mortality rates (HR = 0.51) than non-transfused patients.
Read the article summaryStatin use decreases pneumonia-associated mortality
As published in Critical Care, current statin use was associated with a decreased hospitalization rate and a decreased 30-day mortality rate in patients with pneumonia. The study group consisted of 70,953 patients with pneumonia who were hospitalized for the first time with 10 age- and gender-matched control patients for each pneumonia patient. The OR for pneumonia was 0.80 amongst current statin users compared to non-users; previous statin use had no effect on the risk of pneumonia. The 30-day mortality rates in patients who were statin users and non-users were 11.3% and 15.1%, respectively (HR=0.73).
Read the article summaryMost Popular Anesthesiology Articles
Last month's top read Top Articles of 20121 Nitrous Oxide and Serious Morbidity and Mortality in the POISE Trial Anesthesia & Analgesia, April 29, 2013
2 Anesthetic management of a patient with Huntingtons chorea -A case report- Korean Journal of Anesthesiology, April 1, 2013 Free full text
3 Ryanodine Receptor Type 1 Gene Variants in the Malignant Hyperthermia-Susceptible Population of the United States Anesthesia & Analgesia, April 22, 2013
4 Anesthetic considerations in patients with mitochondrial defects Paediatric Anaesthesia, March 29, 2013
5 From Acupuncture to Interaction between -Opioid Receptors and Na+ Channels: A Potential Pathway to Inhibit Epileptic Hyperexcitability Evidence-based Complementary and Alternative Medicine , April 18, 2013 Free full text Review Article
6 Anaesthesia and airway management in mucopolysaccharidosis Journal of Inherited Metabolic Disease, March 19, 2013
7 Efficacy of the oral neurokinin-1 receptor antagonist aprepitant administered with ondansetron for the prevention of postoperative nausea and vomiting Korean Journal of Anesthesiology, April 15, 2013 Free full text
8 Anesthesia for children with mitochondrial disorders: a national survey and review Journal of Anesthesia, April 10, 2013 Review Article
9
Ketamine Enhances Human Neural Stem Cell Proliferation and Induces Neuronal Apoptosis via Reactive Oxygen Species Mediated Mitochondrial Pathway
Anesthesia & Analgesia, March 22, 2013
Exclusive Author Commentary
10 Sympathetic regulation of cerebral blood flow in humans: a review British Journal of Anesthesia, April 25, 2013 Review Article
11 Bidirectional Regulation of Intravenous General Anesthetic Actions by α3-containing γ-aminobutyric AcidA Receptors Anesthesiology, February 25, 2013
12 Ultrasound imaging for lumbar punctures and epidural catheterisations: systematic review and meta-analysis British Medical Journal, April 10, 2013 Free full text Evidence Based Medicine Review Article
13 Duration of analgesia and pruritus following intrathecal fentanyl for labour analgesia: no significant effect of A118G {mu}-opioid receptor polymorphism, but a marked effect of ethnically distinct hospital populations British Journal of Anesthesia, April 23, 2013
14 Anaesthesia in a child with Rubenstein-Taybi syndrome Southern African Journal of Anaesthesia and Analgesia , April 26, 2013 Free full text
15 Factors Predisposing to Coma and Delirium: Fentanyl and Midazolam Exposure; CYP3A5, ABCB1, and ABCG2 Genetic Polymorphisms; and Inflammatory Factors Critical Care Medicine, March 27, 2013
16 BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state Molecular Pain, April 4, 2013 Free full text
17 CB1 and CB2 Cannabinoid Receptor Agonists Induce Peripheral Antinociception by Activation of the Endogenous Noradrenergic System Anesthesia & Analgesia, January 28, 2013
18 Isoflurane inhibits neutrophil recruitment in the cutaneous Arthus reaction model Journal of Anesthesia, April 10, 2013
19 Sevoflurane suppresses tumour necrosis factor-{alpha}-induced inflammatory responses in small airway epithelial cells after anoxia/reoxygenation British Journal of Anesthesia, March 20, 2013
20 γ-Aminobutyric Acid Receptor Type A Receptor Potentiation Reduces Firing of Neuronal Assemblies in a Computational Cortical Model Anesthesiology, September 25, 2012 Free full text
Indexed Journals in Anesthesiology: Anaesthesia, Anesthesia & Analgesia, Current Anaesthesia and Critical Care more
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