Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adults
Critical Care Medicine, 05/10/2012
Evidence Based Medicine
Parienti JJ et al. – Shortcomings in study design, including channeling, confounding bias, and study heterogeneity, may limit the interpretation of the preliminary study results. The analysis suggests that the subclavian site may be associated with a lower risk of catheter–associated infection. However, a large, randomized, controlled trial comparing each catheter site complication is warranted before the subclavian site can be unequivocally recommended as a first choice for central venous catheter insertion.