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Rapid injection of propofol reduces vascular pain and facilitates Laryngeal Mask Airway insertion
Journal of Clinical Anesthesia, 11/03/2011
Clinical Article
Shimizu T et al. – The rapid administration of propofol reduces pain and facilitates laryngeal mask airway (LMA) insertion versus slow administration of propofol.
Methods- 120 ASA physical status 1 and 2 patients undergoing elective orthopedic surgeries.
- Patients were randomly allocated to one of 4 groups.
- Group A patients were pretreated with normal saline followed by propofol 2.0mg/kg at 3.3mg/sec.
- Group B patients were pretreated with lidocaine 0.5mg/kg followed by propofol 2.0mg/kg at 3.3mg/sec.
- In Group C, patients were pretreated with lidocaine 1.0mg/kg followed by propofol 2.0mg/kg at 3.3mg/sec.
- Group D, patients were pretreated with normal saline followed by propofol 2.0mg/kg at 50mg/sec.
- Pain on injection was measured using a 4–point scale.
- Scale and success rate of smooth LMA insertion also were recorded.
- Rapid injection was less painful than after pretreatment with lidocaine 0.5mg/kg, but was similar to slow injection after pretreatment with lidocaine 1.0mg/kg.
- Rapid injection facilitated LMA insertion, unlike slow injection with lidocaine 0.5mg/kg pretreatment, and was similarly successful to slow injection after pretreatment with lidocaine 1.0mg/kg.
