High-dose dexmedetomidine increases the opioid-free interval and decreases opioid requirement after tonsillectomy in children
Canadian Journal of Anesthesia, 04/07/2011
Pestieau SR et al. – High–dose dexmedetomidine decreases opioid requirements, prolongs the opioid–free interval after tonsillectomy, and prolongs length of stay in the postanesthesia care unit. It is conceivable that these early opioid–sparing effects could benefit patients at risk for respiratory complications early in the postoperative course after tonsillectomy (e.g., patients with obstructive sleep apnea).