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Mashour GA et al. – The incidence of intraoperative awareness with explicit recall is 1–2/1000 cases in the United States. The Bispectral Index monitor is an electroencephalographic method of assessing anesthetic depth. Awareness during general anesthesia is a persistent problem and the role of the Bispectral Index monitor in its prevention is still unclear. The Michigan Awareness Control Study is the largest prospective trial of awareness prevention ever conducted.


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