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Pain: Friend or Foe? A Neurobiologic Perspective: The 2008 Bonica Award Lecture
Regional Anesthesia and Pain Medicine, 11/04/09

Cervero F et al. – Pain is a protective sensation, but it can also be a burden without any useful value. Pain as a friend warns of impending damage and protects the body from injury. Pain as a foe is a useless sensation that makes the underlying problem worse and becomes a disease in its own right. Mechanistically, the systems that mediate good pain and bad pain are often the same, with bad pain being the result of such mechanisms being triggered inappropriately, by irrelevant stimuli or with a time course and intensity disproportionate to the originating cause. We are beginning to know more about the neurobiology of bad pain. The relevant mechanisms are often linked to dysfunction or disease of the nervous system, either of the peripheral nerves or of the central nervous system itself.

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The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: A cross-sectional study
Arthritis Research & Therapy, 11/03/09 Relevance Score: 49%

Pain among Veterans of Operations Enduring Freedom and Iraqi Freedom: Do Women and Men Differ?
Pain Medicine, 10/13/09 Relevance Score: 49%

Prognosis for patients with chronic low back pain: inception cohort study
British Medical Journal, 10/09/09 Relevance Score: 49%

Characterization of chronic pain patients in German pain centers. Core data from more than 10,000 patients
Schmerz, 10/06/09 Relevance Score: 49%

Corticosteroid Injection Treatment to the Ischiadic Spine Reduced Pain in Women With Long-Lasting Sacral Low Back Pain With Onset During Pregnancy: A Randomized, Double Blind, Controlled Trial
Spine, 10/01/09 Relevance Score: 49%