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The Successful Use of Intralipid for Treatment of Local Anesthetic-induced Central Nervous System Toxicity: Some Considerations for Administration of Intralipid in an Emergency
The Clinical Journal of Pain, 10/21/09
Espinet AJ et al. – Intralipid has been proposed as a treatment option for local anesthetic (LA) toxicity, which does not respond to traditional resuscitation methods. This paper presents a case report of a patient who developed signs of local anesthetic toxicity and was subsequently treated with 20% Intralipid with a positive response. Some background and practical applications regarding this treatment are discussed.
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The Role of 20-Hydroxyeicosatetraenoic Acid in Cerebral Arteriolar Constriction and the Inhibitory Effect of Propofol
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