Anesthesia Medical News about Statin prophylaxis

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Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review
Critical Care, 10/27/09

Morgan C et al. – Although the RCT evidence may suggest a reduction in post–CPB inflammation by statin therapy, the evidence is not definitive due to significant limitations. Several of the trials were not methodologically rigorous and statin intervention was highly variable in this small number of studies. This systematic review demonstrates that there is a significant gap that exists in the current literature in regards to the potential anti–inflammatory effect of statin therapy prior to CPB.

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Statin-independent prognosis of patients with diffuse large B-cell lymphoma receiving rituximab plus CHOP therapy
Annals of Oncology, 11/06/09 Relevance Score: 46%

Systematic Review: Comparative Effectiveness and Harms of Combination Therapy and Monotherapy for Dyslipidemia
Annals of Internal Medicine, 11/03/09 Relevance Score: 45%

Statins show dramatic drug and cell dependent effects in the brain
EurekAlert, 10/29/09 Relevance Score: 45%

Skeletal muscle cell MHC I expression: Implications for statin-induced myopathy
Muscle & Nerve, 10/12/09 Relevance Score: 45%

Statin therapy initiated in a man with hepatitis C and elevated cholesterol
The Clinical Advisor, 10/07/09 Relevance Score: 45%