Anesthesia Medical News about dexmedetomidine

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Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis
Journal of Clinical Anesthesia, 10/19/09

Tasdogan M et al. – The objective is to compare the effects of an intravenous infusion of propofol and the alpha–2 adrenoceptor, dexmedetomidine, on inflammatory responses and intraabdominal pressure (IAP) in severe sepsis after abdominal surgery, specifically, serum cytokine levels (interleukin [IL]–1, IL–6, and tumor necrosis factor [TNF]–?) and IAP. Dexmedetomidine infusion decreases TNF–a, IL–1, and IL–6 levels and IAP more than a propofol infusion.

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Prevalence of Delirium with Dexmedetomidine Compared with Morphine Based Therapy after Cardiac Surgery: A Randomized Controlled Trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study)
Anesthesiology, 10/01/09 Relevance Score: 89%

Dexmedetomidine use in a pediatric cardiac intensive care unit: Can we use it in infants after cardiac surgery
Pediatric Critical Care, 11/11/09 Relevance Score: 85%

Dexmedetomidine/ketamine for diagnostic cardiac catheterization in a child with idiopathic pulmonary hypertension
Journal of Clinical Anesthesia, 10/22/09 Relevance Score: 85%

Dexmedetomidine used to provide hypotensive anesthesia during middle ear surgery
Indian Journal of Otolaryngology and Head & Neck Surgery, 10/06/09 Relevance Score: 85%

Dexmedetomidine supplemented with local anesthesia for awake laryngoplasty
Journal of Clinical Anesthesia, 10/19/09 Relevance Score: 84%