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Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation
Cochrane Reviews, 10/27/09

Arrich J et al. – To date about one tenth to a third of successfully resuscitated patients leave hospital to live an independent life again. Clinical studies have shown that this outcome can be improved by cooling the body to about 33°C for several hours after cardiac arrest. The authors found five randomized trials with data on a total of 481 cardiac arrest survivors. With conventional cooling methods patients were more likely to leave hospital without major brain damage and they were more likely to survive to hospital discharge. No cooling specific adverse events were reported. In summary there is currently evidence supporting the use of conventional cooling to induce mild hypothermia in cardiac arrest survivors within the first hours of restoration of spontaneous circulation.

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