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See Latest Articles"Tapentadol" - A Novel Analgesic
Journal of Anaesthesiology Clinical Pharmacology, 10/05/09
Tayal G et al. – Tapentadol is a new analgesic drug with a dual mode of action, hence has efficacy in a broad spectrum of acute and chronic pain models and possibly an improved tolerability profile. It combines moderate mu–opioid agonist activity with NE reuptake inhibition in a single, nonracemic molecule. No metabolic activation of tapentadol is necessary for analgesia, and it has no active metabolites. Further RCTs are needed to establish its routine use in postoperative patients.
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