Anesthesia Medical News about intrathecal fentanyl

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Comparison of intrathecal fentanyl and sufentanil in low-dose dilute bupivacaine spinal anaesthesia for transurethral prostatectomy
British Journal of Anesthesia, 10/01/09

Kim SY et al. – Low–dose diluted bupivacaine with fentanyl 25 microg or sufentanil 5 microg can provide adequate anaesthesia without haemodynamic instability for TURP in elderly patients. However, sufentanil was superior to fentanyl in the quality of the spinal block produced.

Exclusive Author Commentary
H. K. Kil, 10/06/09

It is enough to block the sensory level to T12-L1 in spinal anesthesia for TURP. Especially in elderly patients who have various comorbidity, it is important to limit the block level in avoid to unstable hemodynamic changes. As the result of our study, low-dose dilute bupivacaine (0.25%, 4 mg) with fentanyl 25 mcg or sufentanil 5 mcg provided adequate anesthesia without hemodynamic instability for TURP in erlderly patients. However, sufentanil was superior to fentanyl in the quality of the spinal block produced.

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The effect of intrathecal fentanyl on Cerebral State Index-guided sedation during spinal anaesthesia
Anaesthesia, 11/10/09 Relevance Score: 67%

Spinal mepivacaine with fentanyl for outpatient knee arthroscopy surgery: a randomized controlled trial
Canadian Journal of Anesthesia, 10/29/09 Relevance Score: 65%

A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial
Current Medical Research and Opinion, 10/08/09 Relevance Score: 46%

Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain
Current Medical Research and Opinion, 10/13/09 Relevance Score: 45%

Intrathecal Baclofen Therapy: An Update
PM&R, 10/02/09 Relevance Score: 45%