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Sen H et al. – The addition of paracetamol during IVRA with lidocaine decreased tourniquet pain, increased anesthesia quality, and decreased postoperative analgesic consumption.

Exclusive Author Commentary
Alparslan Turan, 09/23/09

In this article we have used paracetamol as an adjunct to local anesthetic in IVRA. Importance of this study is that it demonstrates a very novel peripheral action of paracetamol on pain. Uptill now the mechanisms of action of paracetamol was believed to be central but this study supports the idea that there may be peripheral action involved in analgesic properties of a very commonly used drug.

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