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Exogenous Il-12 and Its Effect on Th1/Th2 Cell Activity After Cardiac Surgery
Shock, 09/15/09
Franke A et al. – The TH1/TH2 shift after cardiac surgery seems to be caused primarily by a decrease in cellular IFN–gamma synthesis in TH1 lymphocytes. Because TH1 suppression can be reversed by IL–12, it is more likely to be the result of altered stimulation pathways than cellular defects.
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