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See Latest ArticlesGlutamine administration in patients undergoing cardiac surgery and the influence on blood glutathione levels
Acta Anaesthesiologica Scandinavica, 09/08/09
Engel JM et al. – Cardiac surgery with an extracorporeal circulation cardiopulmonary bypass (CPB) is characterized by an oxidative stress response. Glutathione (GSH) belongs to the major antioxidative defense. In metabolic stress, glutamine (GLN) may be the rate–limiting factor of GSH synthesis. Decreased GLN plasma levels were observed after various critical states. A peri–operative high–dose GLN infusion increased plasma GLN concentrations and maintained the GSH levels after cardiac surgery with CPB.
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