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Cardiopulmonary bypass
Anaesthesia & intensive care medicine, 09/10/09
Woods S et al. – The success of cardiac surgery is the result of revolutionary thinking by those who were unafraid to take risks in the 1950s, when cardiopulmonary bypass was in its infancy. Most coronary artery bypass surgery is now performed at normothermia or mild hypothermia, making the argument for alpha–stat or pH–stat blood gas management less critical. Indeed, if the patient has intact cerebral autoregulation (not routinely tested preoperatively), neither pump flow nor pressure influences cerebral blood flow over that autoregulatory range.
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