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See Latest ArticlesThe Reduced Anticoagulant Effect of Fondaparinux at Low Antithrombin Levels
Anesthesia & Analgesia, 08/24/09
Dempfle CE et al. – In the conventional prophylactic and therapeutic dose range, not only treatment with antithrombin concentrates but also an increase in fondaparinux dose normalizes the anticoagulant effect. A saturation effect is observed at high fondaparinux concentrations. Higher levels of antithrombin lead to an exaggerated effect of fondaparinux on Heptest.
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