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Inhibition of nf-[kappa]b activity prevents downregulation of [alpha]1-adrenergic receptors and circulatory failure during clp-induced sepsis
Shock, 08/24/09
Schmidt C et al. – The findings indicate that NF–kB has a central role in augmenting proinflammatory cytokine production during sepsis, which in turn downregulates alpha1–receptor expression. The data further define a critical role for NF–kB in the pathogenesis of septic shock, indicating that targeting NF–kB is a desired therapeutic strategy to treat septic vasoplegia.
Today in Cardiothoracic...keeping you current
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Dexmedetomidine use in a pediatric cardiac intensive care unit: Can we use it in infants after cardiac surgery
Pediatric Critical Care, 11/11/09
Prophylactic Vasopressin in Patients Receiving the Angiotensin-Converting Enzyme Inhibitor Ramipril Undergoing Coronary Artery Bypass Graft Surgery
Journal of Cardiothoracic and Vascular Anesthesia, 11/02/09
A comparison of epidural vs. paravertebral blockade in thoracic surgery
Minerva Anestesiologica, 11/09/09
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Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery
Critical Care, 11/06/09
Inotrope and Vasopressor Therapy of Septic Shock
Critical Care Clinics, 11/09/09
Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: A meta-analysis of randomized controlled trials
Journal of Critical Care, 11/11/09
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