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See Latest ArticlesElectromechanical coupling and regulation of force of cardiac contraction
Anaesthesia & intensive care medicine, 08/04/09
Kirkman E – In contrast to fast skeletal muscle fibres, which need to produce repetitive mechanical action only for short periods before resting, and hence can accrue an oxygen debt, cardiac muscle fibres need to perform repetitive activity for long periods (a lifetime) without rest. Consequently, cardiac muscle fibres are much more dependent on the utilization of oxygen and have an abundance of mitochondria, with rapid oxidation of substrates and formation of ATP, needed for mechanical contraction.
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