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Jain D et al. – Laryngoscopy as well as tracheal intubation cause significant changes in the hemodynamics of the patient. The authors conducted a double blind study to examine the role of Dexmedetomidine on hemodynamic changes during extubation of trachea. A bolus dose of DEX 1microg/kg over 10 minutes, prior to administration of reversal provided hemodynamic stability associated with extubation.This can prove beneficial for cardiac patients where the stress response to extubation is highly undesirable.

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