Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Doctors and the DEA Free full text
Top Ten Searches
epidural double lumen lidoderm scopolamine phenylepherene sciatica est pain control pregnancy intubationYour Article Summary
See Latest ArticlesMu-opioid receptor (A118G) single-nucleotide polymorphism affects alfentanil requirements for extracorporeal shock wave lithotripsy: a pharmacokinetic–pharmacodynamic study
British Journal of Anesthesia, 07/17/09
Ginosar Y et al. - Increased opioid requirement for alfentanil was demonstrated in patients with the G118 SNP, who self-administered a higher dose, achieved higher plasma concentration, and yet complained of more severe pain. This observation suggests that G118 SNP impairs the analgesic response to opioids.
Related Articles
Synthesis and pharmacological properties of a new fluorescent opioid peptide analog
Pharmacological Reports, 10/12/09
Relevance Score: 67%
Morphine/naltrexone extended-release capsules (Embeda): Combination of mu-opioid agonist and mu-opioid antagonist approved for the management of moderate-to-severe pain when continuous analgesia is needed for an extended time period
Formulary, 11/02/09
Relevance Score: 66%
Comparison of the Anti-nociceptive and Anti-Rewarding Profiles of Novel Bifunctional Nociceptin/Orphanin FQ Receptor (NOPr)-Mu Opioid Receptor (MOPr) Ligands: Implications for Therapeutic Applications
Journal of Pharmacology and Experimental Therapeutics, 10/07/09
Relevance Score: 65%
Adolor Corporation Initiates Clinical Testing in Opioid Bowel Dysfunction Program
Adolor Corporation, 11/13/09
Relevance Score: 64%
Tapentadol hydrochloride: A next-generation, centrally acting analgesic with two mechanisms of action in a single molecule
Drugs of Today, 10/19/09
Relevance Score: 62%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Predicting the Unpredictable: A New Prediction Model for Operating Room Times Using Individual Characteristics and the Surgeons Estimate
Anesthesiology, 12/04/09
Clinical relevance of the interleukin 10 promoter polymorphisms in Chinese Han patients with major trauma: genetic association studies
Critical Care, 12/02/09
The Role of 20-Hydroxyeicosatetraenoic Acid in Cerebral Arteriolar Constriction and the Inhibitory Effect of Propofol
Anesthesia & Analgesia, 11/25/09
Today in Pharmacology/kinetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Effects of Dexmedetomidine and Propofol on Lower Esophageal Sphincter and Gastroesophageal Pressure Gradient in Healthy Volunteers
Anesthesiology, 12/04/09
Antagonism of Low Degrees of Atracurium-induced Neuromuscular Blockade: Dose-Effect Relationship for Neostigmine
Anesthesiology, 12/04/09
Article Search
Sponsor