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Comparison of three methods of extra-vascular lung water volume measurement in patients following cardiac surgery
Critical Care, 07/07/09

Maddison B et al. - The principle finding of this study was that the prototype Li-thermal method did not provide reliable measurements of EVLW volume when compared to the ICG-thermal reference technique. Whilst there was minimal bias associated with the single-thermal method, limits of agreement were approximately 45% of the normal value of EVLW volume. The Li-thermal method performed poorly due to the over-estimation of mean indicator transit time using an external lithium ion electrode. These findings suggest the assessment of lung water content by indicator dilution may not be sufficiently reliable for clinical use in individual patients.

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