Anesthesia

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fMRI investigation of the effect of local and systemic lidocaine on noxious electrical stimulation-induced activation in spinal cord
Pain, 06/30/09

Zhao F et al. - This study establishes spinal cord fMRI as a viable assay for analgesics. With respect to the mode of action of lidocaine, this study suggests that systemic lidocaine, which is clinically used for the treatment of neuropathic pain, and believed to only block the peripheral nerve transmission of abnormal neural activity (ectopic discharge) originating from the damaged peripheral nerves, also blocks the peripheral nerve transmission of normal neural activity induced by transcutaneous noxious electrical stimulation.

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Bupivacaine Inhibits Glutamatergic Transmission in Spinal Dorsal Horn Neurons
Anesthesiology, 12/11/09

Guarding Pain and Spontaneous Activity of Nociceptors after Skin versus Skin Plus Deep Tissue Incision
Anesthesiology, 12/11/09

Association of Mitochondrial Allele 4216C With Increased Risk for Sepsis-Related Organ Dysfunction and Shock After Burn Injury
Shock, 12/10/09

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Obstetric analgesia: a comparison of patient-controlled meperidine, remifentanil, and fentanyl in labour
British Journal of Anesthesia, 12/16/09

Lessons Learned with Extended-release Epidural Morphine after Total Hip Arthroplasty
Clinical Orthopedics and Related Research, 12/16/09

Intrathecal baclofen for postoperative analgesia after total knee arthroplasty
Journal of Clinical Anesthesia, 12/15/09

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