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Nefopam and Alfentanil Additively Reduce the Shivering Threshold in Humans whereas Nefopam and Clonidine Do Not
Anesthesiology, 06/26/09
Alfonsi P et al. - Induction of therapeutic hypothermia is often complicated by shivering. Nefopam reduces the shivering threshold with minimal side effects. Nefopam and alfentanil additively reduce the shivering threshold, but nefopam and clonidine do not.
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