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Dexmedetomidine, an 2-adrenergic agonist, inhibits neuronal delayed-rectifier potassium current and sodium current
British Journal of Anesthesia, 07/07/09
Chen B-S et al. - The effects of DEX are not limited to its interactions with alpha2-adrenergic receptors. Inhibitory effects on IK(DR) and INa constitute one of the underlying mechanisms through which DEX and its structurally related compounds might affect neuronal activity in vivo.
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