Anesthesia

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PRO: hydroxyethylstarch can be safely used in the intensive care patient--the renal debate
Intensive Care Medicine, 06/19/09

Boldt J - Hyperoncotic HES should not be used in patients who are at risk of developing kidney dysfunction. In patients without preexisting kidney dysfunction there seems to be no negative effects of modern HES preparations. In septic patients with reduced kidney function HES should be used cautiously, because studies of these patients are not available. Dissolving HES in a balanced solution further improves the safety of HES with regard to kidney function. At present, there seems to be no good reason to generally ban use of HES in the patients.

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Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery
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Osmolarity and partitioning of fluids
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Outcomes following thoracoabdominal resection of neuroblastoma
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