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Ganjoo P et al. - Management of postoperative CSF rhinorrhea can often be problematic. Though a CSF leak may close spontaneously after 1-2 weeks of conservative treatment with bed rest and acetazolamide, many neurosurgeons prefer to intervene early to expedite closure in view of the high mortality rate associated with post-leak meningitis. Surgical intervention with direct dural repair is the ideal closure option, but involves major redo surgery without guaranteed success.

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