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Thiopental Inhibits Lipopolysaccharide-Induced Tissue Factor Expression
Anesthesia & Analgesia, 06/22/09
Hartmann M et al. - During Gram-negative sepsis, lipopolysaccharide (LPS) stimulates toll-like receptor 4, resulting in an activation of the immune system and the expression of tissue factor on monocytes. Thiopental markedly inhibits the LPS-induced tissue factor expression in whole blood samples.
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