Anesthesia Medical News about Deferasirox

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Fanconi Syndrome Due to Deferasirox
American Journal of Kidney Diseases, 06/05/09

Rafat C et al. - The authors report a case of Fanconi syndrome associated with acute renal insufficiency in a patient receiving deferasirox. The latter has to be added to the expanding list of drugs that may induce Fanconi syndrome. Careful monitoring of kidney function and markers of proximal tubular injury are mandatory in patients undergoing treatment with deferasirox.

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Update on the use of deferasirox in the management of iron overload
Therapeutics and Clinical Risk Management, 11/05/09 Relevance Score: 89%

Deferasirox (Exjade) significantly improves cardiac T2* in heavily iron-overloaded patients with beta-thalassemia major
Annals of Hematology, 10/07/09 Relevance Score: 85%

Effects of Chelators (Deferoxamine, Deferiprone and Deferasirox) on the Growth of Klebsiella Pneumoniae and Aeromonas Hydrophila Isolated from Transfusion-Dependent Thalassemia Patients
Hemoglobin, 10/23/09 Relevance Score: 82%

A New Era in Iron Chelation Therapy: The Design of Optimal, Individually Adjusted Iron Chelation Therapies for the Complete Removal of Iron Overload in Thalassemia and other Chronically Transfused Patients
Hemoglobin, 10/23/09 Relevance Score: 80%

Risk/Benefit Assessment, Advantages Over Other Drugs and Targeting Methods in the Use of Deferiprone as a Pharmaceutical Antioxidant in Iron Loading and Non Iron Loading Conditions
Hemoglobin, 10/23/09 Relevance Score: 80%