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Massive Blood Transfusions: The Impact of Vietnam Military Data on Modern Civilian Transfusion Medicine
Anesthesiology, 05/27/09
Miller RD - The authors conclude that clinically important coagulopathies predictably occur after administration of 20-25 units of stored Acid-Citrate-Dextrose blood in acutely wounded, previously healthy soldiers. Fresh frozen plasma should not be a major therapeutic choice for coagulopathies in massive blood transfusions. Treatment of dilutional thrombocytopenia (50,000/mm3) is a primary component of treating coagulopathies associated with massive blood transfusions.
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