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See Latest ArticlesInadequate statistical power to detect clinically significant differences in adverse event rates in randomized controlled trials
Journal of Clinical Epidemiology, 05/14/09
Tsang R et al. - Statistical testing for differences in the proportion of patients experiencing an adverse event is common in RCTs; non–statistically significant differences are associated with low statistical power. A high probability of type II error may lead to erroneous clinical inference resulting in harm. The statistical power for nonsignificant tests should be considered in the interpretation of results.
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