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Perry J et al. - The authors report on a case of systemic capillary leak syndrome associated with a monoclonal band on plasma electrophoresis. Fluid resuscitation, venesection and renal replacement therapy were instituted but a compartment syndrome developed necessitating surgery. The aim is to highlight the difficulties in managing this condition and to remind healthcare workers to include it in the differential diagnoses for patients presenting with polycythaemia; in particular polycythaemic patients with a monoclonal band on plasma electrophoresis.

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