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Boldt J - HES preparations are defined by concentration, molar substitution (MS), mean molecular weight (Mw), the C2/C6 ratio of substitution, the solvent, and the origin. Several studies demonstrated that such modern HES preparations appear to be safe with regard to hemostasis, kidney function, itching, and accumulation. Modern HES preparations are dissolved in balanced, plasma-adapted solutions that no longer contain unphysiological amounts of sodium and chloride and are thus suitable for correcting hypovolemia.

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