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See Latest ArticlesPropofol Produces Immobility via Action in the Ventral Horn of the Spinal Cord by a GABAergic Mechanism
Anesthesia & Analgesia, 04/29/09
Kungys G et al. - Propofol acts in the spinal cord to produce immobility. This depressive effect occurs in the ventral horn and is mediated mainly by GABAA receptors. Isoflurane also depresses neurons in the ventral horn; however, isoflurane actions at the GABAA receptor are either weak or overridden by other effects in the ventral horn.
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