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Design of Recombinant Hemoglobins for Use in Transfusion Fluids
Critical Care Clinics, 04/08/09
Fronticelli C et al. - Introduction of cysteine residues on the hemoglobin surface allows formation of intermolecular bonds and formation of polymeric HBOCs. These polymers of recombinant hemoglobin have the characteristics of molecular size, molecular stability, and oxygen delivery to hypoxic tissue suitable for an HBOC.
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