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The USA Multicenter Prehosptial Hemoglobin-based Oxygen Carrier Resuscitation Trial: Scientific Rationale, Study Design, and Results
Critical Care Clinics, 04/14/09

Moore EE et al. - Patients resuscitated with PolyHeme had outcomes comparable to those receiving the standard of care including rapid access to stored red blood cells. Although there were more adverse events in the PolyHeme group compared with control patients receiving blood, the observed safety profile is acceptable for the intended population. The benefit-to-risk ratio of PolyHeme is favorable when blood is needed but is not available or an option.

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