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Adenosine deaminase that acts on rna 1 p150 in alveolar macrophage is involved in lps-induced lung injury
Shock, 03/24/09
Wu Y et al. - ADAR1 p150 is functionally significant in the development of ALI. It likely exerts its effects in part by mediating the expression of proinflammatory and anti-inflammatory cytokines and influencing tissue neutrophil recruitment and D(A-a)O2. It also implied that ADAR1 inhibitors may help attenuate local inflammatory lung damage.
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