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See Latest ArticlesBeyond clinical phenotype: The biologic integratome
Critical Care Medicine, 01/07/09
Grimaldi D et al. - Network analysis of the biological integratome promises to identify factors that influence disease phenotype, providing unique insight into disease mechanism. Network analysis also provides a mechanistic basis for defining phenotypic differences through consideration of unique genetic and environmental factors that govern intermediate phenotypes contributing to disease expression. Lastly, network analysis offers a unique method for identifying therapeutic targets that can alter disease expression.
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