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Nicorandil, an Adenosine Triphosphate-Sensitive Potassium Channel Opener, Inhibits Muscarinic Acetylcholine Receptor-Mediated Activation of Extracellular Signal-Regulated Kinases in PC12 Cells
Anesthesia & Analgesia, 11/26/08
Niinomi K et al. - Pretreatment of PC12 cells with nicorandil reduced the intracellular Ca2+ concentration stimulated by ACh. Nicorandil inhibits muscarinic activation of the ERK signaling pathway by reducing the intracellular Ca2+ concentration.
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