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Obesity Modestly Affects Inhaled Anesthetic Kinetics in Humans
Anesthesia & Analgesia, 11/26/08
Lemmens HJM et al. - BMI modestly affects FD/FA and FI/FA, and this effect is most apparent for an anesthetic having a greater solubility in all tissues. An increased BMI increases anesthetic uptake and, thus, the need for delivered anesthetic to sustain a constant alveolar anesthetic concentration, particularly with a more soluble anesthetic.
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