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See Latest ArticlesA blinded randomised trial of acupuncture (manual and electroacupuncture) compared with a non-penetrating sham for the symptoms of osteoarthritis of the knee
Acupuncture in Medicine, 07/08/08
Jubb RW et al. - Acupuncture gives symptomatic improvement for patients with osteoarthritis of the knee, and is significantly superior to non-penetrating sham acupuncture.
Methods- Aim was to compare the effect of acupuncture with ‘placebo’ needle in pts with OA knee pain and disability
- Acupuncture naïve pts with OA of the knee received a course of either acupuncture or placebo needle system
- Acupuncture points for pain and stiffness were selected
- Both manual and electrical stimulation were used
- Response was assessed using the WOMAC index for OA of the knee, self reported pain scale, the EuroQol score and plasma β-endorphin
- 34 pts in each group; primary end point was the change in WOMAC pain score after the course of treatment
- Comparison between the 2 treatment groups found a greater improvement with acupuncture vs sham
- Within the acupuncture group there was improvement in pain, which was not seen by those who had sham acupuncture
- Similar effects within group, but not between groups, were seen with the secondary end points of WOMAC stiffness, WOMAC function, and self reported pain
- One month after treatment the between group pain difference had been lost although the acupuncture group was still benefiting vs baseline
- The EuroQol score, a generic measure of HRQol, was not altered by the treatments
- A minority of pts correctly guessed their treatment group
- Plasma β-endorphin levels were not affected by either treatment
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