Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adults

Critical Care Medicine, 05/10/2012

Shortcomings in study design, including channeling, confounding bias, and study heterogeneity, may limit the interpretation of the preliminary study results. The analysis suggests that the subclavian site may be associated with a lower risk of catheter–associated infection. However, a large, randomized, controlled trial comparing each catheter site complication is warranted before the subclavian site can be unequivocally recommended as a first choice for central venous catheter insertion.

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