Statin therapy as prevention against development of acute respiratory distress syndrome
Critical Care Medicine, 05/01/2012Bajwa EK et al.
Statin therapy at the time of intensive care unit admission was not associated with a lower rate of development of acute respiratory distress syndrome after matching for patient propensity to receive statins. Statin therapy was not associated with improvements in acute respiratory distress syndrome mortality, organ failure, or days free from mechanical ventilation.
Patients were followed–up for the primary outcome of acute respiratory distress syndrome and secondary outcomes of intensive care unit and 60–day mortality, organ dysfunction, and ventilator–free days in a secondary analysis of a prospective cohort study.
Receipt of statin therapy was recorded.
Propensity score matching was used to adjust for confounding by indication.
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