Is there still a place for vasopressors in the treatment of cardiac arrest

Critical Care, 04/10/2012

Two recent controlled trials in out–of–hospital cardiac arrest patients demonstrated that administration of epinephrine and other drugs was associated with a significant increase in short–term survival but not in survival to hospital discharge. In one of those trials, patients in the epinephrine group had more than twice the odds of surviving to hospital discharge than those who received placebo, but the difference did not reach statistical significance, possibly because of inadequate sample size.

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