The Crystalloid versus Hydroxyethyl Starch Trial: protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality

Intensive Care Medicine, 02/15/2011

The study run–in phase has been completed and the main trial commenced in April 2010. Crystalloid versus Hydroxyethyl Starch Trial (CHEST) should generate results that will inform and influence prescribing of this commonly used resuscitation fluid.

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