Factors contributing to large analgesic effects in placebo mechanism studies conducted between 2002 and 2007 Vase L et al. - These results replicate the authors' previous finding that placebo analgesic effects are higher in mechanism studies than in placebo control studies. However, since magnitudes of placebo analgesic effects are highly variable it may be valuable to investigate the factors and mechanisms that contribute to this variability as well as differences in magnitudes across types of studies. [more...]