Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis Arnold RC et al. - The authors sought to determine if early lactate clearance is associated with improved survival in emergency department patients with severe sepsis and the concordance between central venous oxygen saturation (ScvO2) optimization and lactate clearance during early sepsis resuscitation. The data provide rationale for a clinical trial of lactate clearance as a distinct end point of early sepsis resuscitation. [more...]
