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Isotonic and hypertonic crystalloid solutions in the critically ill
Best Practice & Research - Clinical Anaesthesiology, 06/16/09
Bauer M et al. - Crystalloid resuscitation is superior to vasopressors in shock associated with blunt trauma, and is at least not inferior to colloids in septic shock. Traditional rules of thumb indicating the need for three to four times the amount of crystalloids for the plasma volume to be replaced are probably erroneous and might have contributed to association of overly aggressive crystalloid resuscitation with poor outcome.
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